Thomas Shepard (5 November 1605 – 25 August 1649) was an English, afterwards American Puritan minister and a significant figure in early colonial New England.
Shepard was regarded as one of the foremost Puritan ministers of his day, esteemed in the company of individuals like Richard Mather and John Cotton. He took special interest in Puritan ministry to the Massachusetts Native Americans. His written legacy includes an autobiography and numerous sermons, which in some measure of contrast with others of his day, tended to accent God as an accessible and welcoming figure in the individual life. Today a plaque at Harvard University, in the words of Cotton Mather, records that it was in consideration of the salutary effect of Shepard’s ministry that the college ultimately came to be placed in “Newtowne”, known today as Cambridge, Massachusetts.